Aim. The pur pose of this study is to r eview studies that have investigated the effect of Car dioPulmonary Cerebral Resuscitation (CPCR) training on nurses' knowledge and performance. Background. CPCR is a systematic pr ocedur e and a set of tar geted measur es have been used by nurses to restore the vital functions of the body's central organs, such as the heart, lungs, and brain. The application of teaching is a suggested method for improving the knowledge and skills of nurses PCPR in most published articles. Method. In this r eview study, a compr ehensive sear ch of scientific databases and sear ch engines such as Science Direct, PubMed, Cochrane, Medline, SID, Scopus, CINAHL, OVID, Iran Doc and Magiran using the keywords cardiopulmonary resuscitation, nurses, practice, knowledge in both Persian and English languages was done to find articles published between 2010 and 2022. Results: CPCR tr aining in both face-to-face and virtual form can be effective on the knowledge and performance of nurses, and in all studies there was a significant relationship between the scores before and after the training. The implementation of these trainings should be repeated for nurses permanently and every six months. Conclusion: Basic tr aining can lead to incr easing the knowledge of nur ses in the field of basic and advanced cardiopulmonary resuscitation. Based on this, regular theoretical and practical workshops and training courses are recommended.